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  • Decades-old question about protein found in Alzheimer's brain plaques

    Jeudi, 10 janvier 2019 14:17:55 De: Sciencedaily Dernière modification: Mercredi, 23 janvier, 2019 - 20:43

    Alzheimer's-affected brains are riddled with so-called amyloid plaques: protein aggregates consisting mainly of amyloid-beta. However, this amyloid-beta is a fragment produced from a precursor protein whose normal function has remained enigmatic for decades. A team of scientists has now uncovered that this amyloid precursor protein modulates neuronal signal transmission through binding to a specific receptor. Modulating this receptor could potentially help treat Alzheimer's or other brain diseases.